The cell membranes of cancer cells differ from those of healthy cells in a number of ways. One striking feature is the presence of negatively charged lipids on the outside of the tumour cell membrane - a difference that can be exploited in a targeted manner. Our research is developing positively charged peptides derived from the human defence system that selectively interact with these tumour cell membranes without damaging healthy cells.

We use various biophysical methods to optimize the efficacy and safety of these peptides. Spectroscopy, microscopy and analytical methods help us to understand the interaction of the peptides with cell membranes at the molecular level. Realistic toxicity studies and precise analyses make it possible to further develop the peptides for safe and effective application.

Our vision is to pave entirely new paths in cancer therapy by combining Cancer Biophysics with innovative peptide technologies. We aim to uncover the Achilles' heel of cancer cells and develop new therapies that eliminate tumor cells precisely and selectively.