10 selected publications in the field of antitumour research
Pasupuleti, R., Riedl S., Núñez, LS., Karava, M., Kumar, V., Kourist, R., Turnbull, WB., Zweytick, D.*, Wiltschi, B.* Lectin-anticancer peptide fusion demonstrates significant cancer-cell-selective cytototoxic effect and inspires the production of 'clickable' anticancer peptide in E. coliProtein Science ( 2023) 32(12):e4830. doi: 10.1002/pro.4830.
Wußmann, M., Groeber-Becker, FG., Riedl S., Alihodzic, D., Padaric, D., Gerlitz, L., Stallinger, A., Liegl-Atzwanger, B., Zweytick, D.*, Rinner B.* In Model, In Vitro and In Vivo Killing Efficacy of Antitumor Peptide RDP22 on MUG-Mel2, a Patient Derived Cell Line of an Aggressive Melanoma Metastasis. Biomedicine (2022) 10(2961): 1-23. doi: 10.3390/biomedicines10112961
Maxian T., Gerlitz L., Riedl S.*, Rinner B. and Zweytick D.* Effect of L- to D-Amino Acid Substitution on Stability and Activity of Antitumor Peptide RDP215 against Human Melanoma and Glioblastoma. Int J Mol Sci (2021) 22(16): 8469. doi: 10.3390/ijms22168469
Grissenberger S., Riedl S., Rinner B., Leber R.*, Zweytick D.* Design of Human Lactoferricin Derived Antitumour Peptides-Activity and Specificity Against Malignant Melanoma in 2D and 3D Model Studies. biochim. Biophys. Acta (2020) 1862(8): 183264. doi.org/10.1016/j.bbamem.2020.183264
Wodlej C., Riedl S.*, Rinner B., Leber R., Drechsler C., Voelker DR., Choi J-Y., Lohner K. and Zweytick D.* Interaction of two Antitumour Peptides with Membrane Lipids - Influence of Phosphatidylserine and Cholesterol on Specificity for Melanoma Cells PLoS One (2019) 14(1): e0211187.; eCollection 2019. doi: 10.1371/journal.pone.0211187
Riedl S., Rinner B.*, Schaider H., Liegl-Atzwanger B., Meditz K., Preishuber-Pflügl J., Grissenberger S., Lohner K. and Zweytick D.* In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumour peptide R-DIM-P-LF11-334 on human malignant melanoma Oncotarget (2017) 8( 42):71817-71832. doi: 10.18632/oncotarget.17823.
Riedl S., Leber R., Rinner B., Schaider H., Lohner K. and Zweytick D.* Human lactoferricin derived di-peptides deploying loop structures induce apoptosis specifically in cancer cells through targeting membranous phosphatidylserine. Biochim. Biophys. Acta (2015) 1848:2918-2931. doi: 10.1016/j.bbamem.2015.07.018
Riedl S., Rinner B., Schaider H., Lohner K. and Zweytick D.* Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine. Biometals (2014) 27(5):981-997. doi: 10.1007/s10534-014-9749-0.
Riedl S., Rinner B., Asslaber M., Schaider H., Walzer S., Novak A., Lohner K. and Zweytick D.* In search of a novel target - Phosphatidylserine exposed by non-apoptotic tumour cells and metastases of malignancies with poor treatment efficacy. Biochim. Biophys. Acta (2011) 1808:2638-2645. doi: 10.1016/j.bbamem.2011.07.026.
Zweytick D.*, Tumer S., Blondelle S.E. and Lohner K. Membrane curvature stress and antibacterial activity of lactoferricin derivatives. Biochem. Biophys. Res. Comm. (2008) 369:395-400. doi: 10.1016/j.bbrc.2008.01.176.
*corresponding author(s)